3/98-10/01 – Ph.D. in the lab of Prof. Jacqueline Trotter;
"Signaltransduction to the Cytoskeleton of Oligodendrocytes
during early Myelination".
10/92-12/97 – Study of Biology at the University of
Heidelberg, Germany.
Interests
I am interested in the biology of neural
stem cells. Neural stem cells have been identified in various
regions of the CNS. Several studies have suggested that during
embryonic development radial glia cells may act as stem cells.
In the forebrain, radial glia cells have been shown to give
rise to neurons both in vitro and in vivo. The Notch signaling
pathway seem to play a crucial role by either maintaining
or promoting stem cell properties in the forebrain. I am interested
in defining the radial glia stem cell population closer by
taking advantage of a mouse expressing the green fluorescent
protein under the promotor of the radial glia cell marker
BLBP (brain specific lipid binding protein). In addition I
plan to fate map radial glia cells by using the BLBP promotor
and expressing an inducible form of cre enabling the temporal
control of recombination events.
