Contact Information

Email jayshree.samanta@med.nyu.edu

Education & Training

Ph.D. Northwestern University 2006, Lab of John A. Kessler.

Current Work

The presence of demyelinated axons within the central nervous system (CNS) is the hallmark of Multiple sclerosis(MS) and a major cause of morbidity. It has long been known that new myelin sheaths can be formed through spontaneous remyelination. However, remyelination is insufficient in MS and the reasons for this failure are not well-understood. Recent studies indicate that progenitor cells in the SVZ are activated in brains of MS patients. I am using various mouse models to study the role of Sonic Hedgehog signaling during remyelination.