Publications 1995-1991

Kim, N. and Burden, S.J. 2008. MuSK controls where motor axons grow and form synapses. Nature Neuroscience 11:19-27.

Friese, M.B., Blagden, C.S. and Burden, S.J. 2007. Synaptic differentiation is defective in mice lacking acetylcholine receptor beta subunit tyrosine phosphorylation. Development 134:4167-4176.

Mammucari, C., Milan, G., Romanello, V., Masiero, E., Rudolf, R., Del Piccolo, P., Burden, S.J., Di Lisi, R., Sandri, C., Zhao, J., Goldberg, A.L., Schiaffino, S. and Sandri, M. 2007. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metabolism 6:458-471.

Jones, N., Hardy, W.R., Friese, M.B., Jorgensen, C., Smith, M.J., Woody, N.N., Burden, S.J., and Pawson, T. 2007. Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with Muscle-Specific Kinase (MuSK). Mol. Cell. Biol. 27:4759-4773.

Jaworski, A., Smith, C.L. and Burden, S.J. 2007. GA-binding protein is dispensable for neuromuscular synapse formation and synapse-specific gene expression. Mol. Cell. Biol. 27:5040-5046.

Stiegler, A.L., Burden, S.J., and Hubbard, S.R. 2006. Crystal structure of the Agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK. J. Mol. Biol. 364:424-433.

Jevesk, M., Jaworski, A., Polo-Parada, L., Kim, N., Fan, J., Landmesser, L.T., and Burden, S.J. 2006. CD24 is expressed by myofiber synaptic nuclei and regulates synaptic transmission. Proc Natl Acad Sci USA. 103: 6374-6379.

Jaworski, A. and Burden, S.J. 2006. Neuromuscular synapse formation in mice lacking neuron- and skeletal muscle-derived Neuregulin-1. J. Neurosci. 26:655-661.

Wang, X., Blagden, C., Fan, J., Nowak, S., Taniuchi, I., Littman, D.R. and Burden, S.J. 2005. Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle. Genes & Development 19:1715-1722.

Mittaud, P., Camilleri, A.A., Willmann, R., Erb-Vogtli, S., Burden, S.J. and Fuhrer, C. 2004. A single pulse of agrin triggers a pathway that acts to cluster acetylcholine receptors. Mol. Cell. Biol. 24:7841-7854.

Rimer, M., Prieto, A.L., Weber, J.L., Colasante, C., Ponomareva, O., Fromm, L., Schwab, M.H., Lai, C. and Burden, S.J. 2004. Neuregulin-2 is synthesized by motor neurons and terminal Schwann cells and activates acetylcholine receptor transcription in muscle cells expressing ErbB4. Mol. Cell. Neurosci. 16:271-281.

Blagden, C.S., Fromm, L. and Burden, S.J 2004. Accelerated response of the myogenin gene to denervation in mutant mice lacking phosphorylation of myogenin at threonine 87. Mol. Cell. Biol. 24:1983-1989.

Burden SJ, Fuhrer C, Hubbard SR.2003. Agrin/MuSK signaling: willing and Abl. Nat Neurosci. 6:653-654.

Hippenmeyer, S., Shneider, N.A., Birchmeier, C., Burden, S.J., Jessell, T.M. and Arber, S. 2002. A role for Neuregulin-1 signaling in muscle spindle differentiation. Neuron 36:1035-1049
.

Herbst, R., Avetisova, E. and Burden, S.J. 2002. Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor. Development 129:5449-5460.

Watty, A. and Burden, S.J. 2002. N-linked glycosylation of MuSK restrains ligand-independent MuSK activation and AChR clustering. J. Biol. Chem. 277:50457-50462.

Burden, S.J., Berg, D.K. and O’Leary, D.M. 2002. Target selection and synapse formation. In: Fundamental Neuroscience, Acad. Press, pp. 469-498.

Wredenberg, A., Wibom, R., Wilhelmsson, H., Graff, C., Wiener, H.H., Burden, S.J., Oldfors, A., Westerblad, H. and Larsson, N.G. 2002. Increasedmitochondrial mass in mitochondrial myopathy mice. Proc. Natl. Acad. Sci.
USA 99:15066-15071.

Arber, S., Burden, S.J. and Harris, A.J. 2002.
Patterning of skeletal muscle. Curr. Opin. Neurobiol. 12:100-103.

Burden, S.J. 2002. Building the vertebrate neuromuscular synapse. J. Neurobiol. 53:501-511.

Yang, X., Arber, S., William, C., Li, L., Tanable, Y., Jessell, T.M., Birchmeier, C. and Burden, S.J. 2001. Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron 30:399-410.

Fromm, L. and Burden, S.J. 2001. Neuregulin-1-stimulated phosphorylation of GABP in skeletal muscle cells. Biochemistry 40:5306-5312.

Smith, C.L., Mittaud, P., Prescott , E.D., Fuhrer, C. and Burden, S.J. 2001. Src, Fyn and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors. J. Neuroscience 21:3151-3160.

Watty, A., Neubauer, G., Dreger, M., Zimmer, M., Wilm, M. and Burden, S.J. 2000. The in vitro and in vivo phosphotyrosine map of activated MuSK. Proc. Natl. Acad. Sci. USA. 97:4585-4590.

Bothe, G.W.M., Haspel, J.A., Smith, C.L., Wiener, H.H. and Burden, S.J. 2000. Selective expression of Cre recombinase in skeletal muscle fibers. Genesis 26:165-166.


Burden, S.J. 2000. Wnts as retrograde signals for axon and growth cone differentiation. Cell 100:495-497.

Herbst, R. and Burden, S.J. 2000. The juxtamembrane region of MuSK has a critical role in agrin-mediated signaling. EMBO J. 19:67-77.

Yang, X., Li, W., Prescott , E.D., Burden, S.J., and Wang, J.C. 2000. DNA topoisomerase IIb and neural development. Science 287:131-134.

Lichtman, J.W., Burden, S.J., Culican, S.M. and Wong, R.O.L. 1999. Synapse formation and elimination. In: Fundamental Neuroscience, Acad. Press, pp. 547-580.


Fromm, L. and Burden, S.J. 1998. Transcriptional pathways for synapse-specific, neuregulin-induced and electrical activity-dependent transcription. J. Physiol. ( Paris ) 92:173-176.

Fromm, L. and Burden, S.J. 1998. Synapse-specific and neuregulin-induced transcription require an Ets site that binds GABPa/GABPb. Genes and Development 12:3074-3083.

Rimer, M., Cohen, I. , Lømo, T., Burden, S.J., and McMahan, U.J. 1998. Neuregulins and erbB receptors at neuromuscular junctions and at agrin-induced postsynaptic-like apparatus in skeletal muscle. Mol. Cell. Neurosci. 12:1-15.

Burden, S.J. 1998. The formation of neuromuscular synapses. Genes and Development 12:133-148.


Burden, S.J. and Yarden, Y. 1996. Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis. Neuron 18:847-855.

Glass, D.J., Bowen , D.C. , Radziejewski, C., Bruno. J., Stitt, T.N., Ryan, T.E., Gies, D.R., Mattsson, K., Shah, S., Burden, S.J., Valenzuela, D.M., DeChiara, T.M., and Yancopoulos, G.D. 1996. Agrin acts vis a MuSK receptor complex. Cell 85:513-523.


DeChiara, T.M., Bowen , D.C. , Valenzuela, D.M., Simmons, M.V., Poueymirou, W.T., Thomas, S., Kinetz, E., Compton , D.L., Park, J.S., Smith, C., DiStefano, P.S., Glass, D.J., Burden, S.J. and Yancopoulos, G.D. 1996. The receptor tyrosine kinase, MuSK, is required for neuromuscular junction formation in vivo. Cell 85:501-512.

 

 

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