SKIRBALL INSTITUTE Skirball Institute NYU School of Medicine New York University
OF BIOMOLECULAR MEDICINE


Gan Lab Publications

  1. Pan F, Gan WB. (2008) Two-photon imaging of dendritic spine development in the mouse cortex. Developmental Neurobiology 68(6):771-8. | PDF

  2. Xu HT, Pan F, Yang G, Gan WB. (2007) Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex. Nature Neuroscience 10(5):549-51. | PDF

  3. Grutzendler J, Helmin K, Tsai J, Gan WB. (2007) Various dendritic abnormalities are associated with fibrillar amyloid deposits in Alzheimer's disease. Annals of the New York Academy of Sciences 1097:30-39. | PDF

  4. Bi GQ, Bolshakov V, Bu G, Cahill CM, Chen ZF, Collingridge GL, Cooper RL, Coorssen JR, El-Husseini A, Galhardo V, Gan WB, Gu J, Inoue K, Isaac J, Iwata K, Jia Z, Kaang BK, Kawamata M, Kida S, Klann E, Kohno T, Li M, Li XJ, MacDonald JF, Nader K, Nguyen PV, Oh U, Ren K, Roder JC, Salter MW, Song W, Sugita S, Tang SJ, Tao Y, Wang YT, Woo N, Woodin MA, Yan Z, Yoshimura M, Xu M, Xu ZC, Zhang X, Zhen M, Zhuo M. (2006) Recent advances in basic neurosciences and brain disease: from synapses to behavior. Molecular Pain 2:38. | PDF

  5. Haynes SE, Hollopeter G, Yang G, Kurpius D, Dailey ME, Gan WB, Julius D. (2006) The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nature Neuroscience 9(12):1512-9. | PDF

  6. Grutzendler J, Gan WB. (2006) Two-photon imaging of synaptic plasticity and pathology in the living mouse brain. NeuroRX 3(4):489-96. | PDF

  7. Zhang ZG, Zhang L, Ding G, Jiang Q, Zhang RL, Zhang X, Gan WB, Chopp M. (2005) A model of mini-embolic stroke offers measurements of the neurovascular unit response in the living mouse. Stroke 36(12):2701-4. | PDF

  8. Zuo Y, Yang G, Kwon E, Gan WB. (2005) Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex. Nature 436(7048):261-5. | PDF

  9. Yang G, Gong YD, Gong K, Jiang WL, Kwon E, Wang P, Zheng H, Zhang XF, Gan WB, Zhao NM. (2005) Reduced synaptic vesicle density and active zone size in mice lacking amyloid precursor protein (APP) and APP-like protein 2. Neuroscience Letters 384(1-2):66-71. | PDF

  10. Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, Jung S, Littman DR, Dustin ML, Gan WB. (2005) ATP mediates rapid microglial response to local brain injury in vivo. Nature Neuroscience 8(6):752-8. | PDF

  11. Zuo Y, Lin A, Chang P, Gan WB. (2005) Development of long-term dendritic spine stability in diverse regions of cerebral cortex. Neuron 46(2):181-9. | PDF

  12. Wang P, Yang G, Mosier DR, Chang P, Zaidi T, Gong YD, Zhao NM, Dominguez B, Lee KF, Gan WB, Zheng H. (2005) Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2. Journal of Neuroscience 25(5):1219-25. | PDF

  13. Li Q, Lee JS, Ha C, Park CB, Yang G, Gan WB, Chang YT. (2004) Solid-phase synthesis of styryl dyes and their application as amyloid sensors. Angew Chem Int 43(46):6331-5. | PDF

  14. Bishop DL, Misgeld T, Walsh MK, Gan WB, Lichtman JW. (2004) Axon branch removal at developing synapses by axosome shedding. Neuron 44(4):651-61. | PDF

  15. Tsai J, Grutzendler J, Duff K, Gan WB. (2004) Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches. Nature Neuroscience 7(11):1181-3. | PDF

  16. Sadowski M, Pankiewicz J, Scholtzova H, Tsai J, Li Y, Carp RI, Meeker HC, Gambetti P, Debnath M, Mathis CA, Shao L, Gan WB, Klunk WE, Wisniewski T. (2004) Targeting prion amyloid deposits in vivo. Journal of Neuropathology & Experimental Neurology 63(7):775-84. | PDF

  17. Gan WB, Kwon E, Feng G, Sanes JR, Lichtman JW. (2003) Synaptic dynamism measured over minutes to months: age-dependent decline in an autonomic ganglion. Nature Neuroscience 6(9):956-60. | PDF

  18. Gan WB. (2003) Glutamate-dependent stabilization of presynaptic terminals. Neuron 38(5):677-8. | PDF

  19. Grutzendler J, Tsai J, Gan WB. (2003) Rapid labeling of neuronal populations by ballistic delivery of fluorescent dyes. Methods 30(1):79-85. | PDF

  20. Grutzendler J, Kasthuri N, Gan WB. (2002) Long-term dendritic spine stability in the adult cortex. Nature 420(6917):812-6. | PDF

  21. Kettunen P, Demas J, Lohmann C, Kasthuri N, Gong Y, Wong RO, Gan WB. (2002) Imaging calcium dynamics in the nervous system by means of ballistic delivery of indicators. Journal of Neuroscience Methods 119(1): 37-43. | PDF

  22. Keller-Peck, C.R., Walsh, M.K., Gan, WB., Feng, G., Sanes, J.R., Lichtman, J.W. (2001) Asynchronous synapse elimination in neonatal motor units: studies using GFP transgenic mice. Neuron 31:381-94. | PDF

  23. Gan, WB., Grutzendler, J., Wong, WT., Wong, R.O.L., Lichtman, J.W. (2000) Multicolor “DiOlistic” labeling of neuronal circuits using lipophilic dye combinations. Neuron 27: 219-225. | PDF

  24. Gan WB. TrkB works at postsynaptic sites. Neuron. 1999 Nov;24(3):491-2. | PDF

  25. Gan WB, et al. Vital imaging and ultrastructural analysis of individual axon terminals labeled by iontophoretic application of lipophilic dye. J Neurosci Methods. 1999 Oct 30;93(1):13-20. | PDF

  26. Gan WB, et al. Cellular expression of a leech netrin suggests roles in the formation of longitudinal nerve tracts and in regional innervation of peripheral targets. J Neurobiol. 1999 Jul;40(1):103-15. | PDF

  27. Gan WB, et al. Synaptic segregation at the developing neuromuscular junction. Science. 1998 Nov 20;282(5393):1508-11. | PDF

  28. Gan WB, et al.Competition among the axonal projections of an identified neuron contributes to the retraction of some of those projections. J Neurosci. 1997 Jun 1;17(11):4293-301. | PDF

  29. Wong VY, et al. The leech homeobox gene Lox4 may determine segmental differentiation of identified neurons. J Neurosci. 1995 Aug;15(8):5551-9. | PDF

  30. Gan WB, et al. Developing neurons use a putative pioneer's peripheral arbor to establish their terminal fields. J Neurosci. 1995 May;15(5 Pt 1):3254-62. | PDF

  31. Gan WB, et al. Interactions between segmental homologs and between isoneuronal branches guide the formation of sensory terminal fields. J Neurosci. 1995 May;15(5 Pt 1):3243-53. | PDF

  32. Becker T, et al. Target-induced neurogenesis in the leech CNS involves efferent projections to the target. Development. 1995 Feb;121(2):359-69. | PDF