Sims, T.N., T.J. Soos, H.S. Xenias, B. Dubin-Thaler, J.M. Hofman, J.C. Waite, T.O. Cameron, V.K. Thomas, R. Varma, C.H. Wiggins, M.P. Sheetz, D.R. Littman, and M.L. Dustin. Opposing Effects of PKCtheta and WASp on Symmetry Breaking and Relocation of the Immunological Synapse. Cell 2007; 129, 773-785.

Mor, A., G. Campi, G. Du, Y. Zheng, D.A. Foster, M.L. Dustin, and M.R. Philips. 2007. The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2. Nat Cell Biol 2007; ncb1592.

Schwickert, T. A., Lindquist, R. L., Shakhar, G., Livshits, G., Kosco-Vilbois, M. H., Dustin*, M. L., and Nussenzweig*, M. C. Germinal center imaging reveals a dynamic open structure. Nature 2007; 446:83-7.

Alon, R., and M.L. Dustin. Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. Immunity 2007; 26:17-27.

Zhu, D. M., M. L. Dustin, C. W. Cairo, and D. E. Golan. Analysis of two-dimensional dissociation constant of laterally mobile cell adhesion molecules. Biophys J 2007; 92:1022-23.

Zhu, D. M., Dustin, M. L., Cairo, C. W., Thatte, H. S., and Golan, D. E. Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion. ACS Chem Biol 2006; 1:649-658.

Demond, A. L., Starr, T., Dustin, M. L., and Groves, J. T. Control of antigen presentation with a photoreleasable agonist Peptide. J Am Chem Soc 2006; 128:15354-15355.

Anikeeva, N., Lebedeva, T., Clapp, A. R., Goldman, E. R., Dustin, M. L., Mattoussi, H., and Sykulev, Y. Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response. Proc Natl Acad Sci U S A 2006; 103:16846-16851.

Döbereiner, H. G., B. J. Dubin-Thaler, J. Hofman, H. S. Xenias, T. N. Sims, G. Giannone, M. L. Dustin, C. Wiggins and M. P. Sheetz. Lateral Membrane Waves Constitute a Universal Dynamic Pattern of Motile Cells. Phys. Rev. Letters, 2006; 97, 38102-1-4.

Kim, J., and M.L. Dustin. Innate response to focal necrotic injury inside the blood brain barrier. J. Immunol., 2006; 177:5269-5277.

Varma, R., G. Campi, T. Yokosuka, T. Saito and M.L. Dustin. T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity, 2006; 25, 117-127.

Dustin, M.L. Immunology. When F-actin becomes too much of a good thing. Science, 2006; 313, 767-768.

Dustin, M.L. Impact of the immunological synapse on T cell signaling. Results Probl Cell Differ 2006; 43:175-198.

Dustin, M.L., and C. Zhu. T cells like a firm molecular handshake. Proc Natl Acad Sci U S A, 2006; 103, 4335-4336.

Soos, T.J., T.N. Sims, L. Barisoni, K. Lin, D.R. Littman, M.L. Dustin, and P.J. Nelson. CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney. Kidney Int, 2006; 70, 591-596.

Dustin, M.L., S.Y. Tseng, R. Varma, and G. Campi. T cell-dendritic cell immunological synapses. Curr Opin Immunol, 2006; 18, 512-516.

Germain, R. N., M. J. Miller, M.l L. Dustin, and M C. Nussenzweig. Dynamic Imaging of the Immune System: Progress, Pitfalls, and Promise. Nat. Rev. Immunol., 2006; 6, 497-507.

Tadakoro, C.E., G. Shakhar, S. Shen, Y. Ding, A.C. Lino, A. Maraver, J.J. Lafaille*, and M.L. Dustin*. Regulatory T cell inhibit stable contacts between CD4+ T cells and dendritic cells in vivo. J. Exp. Med. 2006; 203:505-511.

Mossman, K., G. Campi, J.T. Groves* and M.L. Dustin*. Altered TCR signaling from geometrically repatterned immunological synapses. Science. 2005; 310, 1191-1193.

Tseng, S.Y., M. Liu, and M.L. Dustin. CD80 cytoplasmic domain controls the localization of CD28, CTLA-4 and PKC-q in the immunological synapse. J.Immunol. 2005; 175, 7829-7836.

Shakhar G, Lindquist RL, Skokos D, Dudziak D, Huang JH, Nussenzweig MC, Dustin ML. Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo.. Nat Immunol. 2005 Jul;6(7):707-14.

Campi G, Varma R, Dustin ML.Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J Exp Med. 2005 Oct 17;202(8):1031-6.

Lindquist RL, Shakhar G, Dudziak D, Wardemann H, Eisenreich T, Dustin ML, Nussenzweig MC. (2004). Visualizing dendritic cell networks in vivo. Nat Immunol. 5(12):1243-50.

Dustin ML. Stop and go traffic to tune T cell responses. Immunity. 2004 Sep;21(3):305-14. Review.

Somersalo, K., Anikeeva, N., Sims, T.N., Thomas, V.K., Strong, R.K., Spies, T., Lebedeva, T., Sykulev, Y., and Dustin, M.L. (2004). Cytotoxic T lymphocytes form an antigen-independent ring junction. J Clin Invest 113, 49-57.

Heissmeyer, V., Macian, F., Im, S.H., Varma, R., Feske, S., Venuprasad, K., Gu, H., Liu, Y.C., Dustin, M.L., and Rao, A. (2004). Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins. Nat Immunol 5, 255-265.

Dustin, M.L., Bivona, T.G., and Philips, M.R. (2004). Membranes as messengers in T cell adhesion signaling. Nat Immunol 5, 363-372.

Davis, D.M., and Dustin, M.L. (2004). What is the importance of the immunological synapse? Trends Immunol 25, 323-327.

Carrasco, Y.R., Fleire, S.J., Cameron, T., Dustin, M.L., and Batista, F.D. (2004). LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation. Immunity 20, 589-599.

Lee, K.H., Dinner, A.R., Tu, C., Campi, G., Raychaudhuri, S., Varma, R., Sims, T.N., Burack, W.R., Wu, H., Wang, J., Kanagawa, O., Markiewicz, M., Allen, P.M., Dustin, M.L., Chakraborty, A.K., and Shaw, A.S. (2003). The immunological synapse balances T cell receptor signaling and degradation. Science 302, 1218-1222.

Groves, J.T., and Dustin, M.L. (2003). Supported planar bilayers in studies on immune cell adhesion and communication. J Immunol Methods 278, 19-32.

Dustin, M.L. (2003). Coordination of T cell activation and migration through formation of the immunological synapse. Ann N Y Acad Sci 987, 51-59.

Dustin, M.L. (2003). In vivo imaging approaches in animal models of rheumatoid arthritis. Arthritis Res Ther 5, 165-171.

Chakraborty, A.K., Dustin, M.L., and Shaw, A.S. (2003). In silico models for cellular and molecular immunology: successes, promises and challenges. Nat Immunol 4, 933-936.

Hailman, E., Burack, W.R., Shaw, A.S., Dustin, M.L., and Allen, P.M. (2002). Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation. Immunity 16, 839-848.

Dustin ML and Colman DR: Neural and immunological synaptic relations.Science 2002, 298: 785-789.

Hailman E, Burack WR, Shaw AS, Dustin ML, and Allen PM: Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation. Immunity 2002, 16: 839-848.

Dustin ML: Shmoos, rafts, and uropods- the many facets of cell polarity. Cell 2002, 110: 13-18.

Burack WR, Lee KH, Holdorf AD, Dustin ML, and Shaw AS: Cutting edge: quantitative imaging of raft accumulation in the immunological synapse. J Immunol 2002, 169: 2837-2841.

Sims TN and Dustin ML: The immunological synapse: integrins take the stage. Immunol Rev 2002, 186: 100-117.

Dustin ML: Membrane domains and the immunological synapse: keeping T cells resting and ready. J Clin Invest 2002, 109: 155-160.

Savage ND, Kimzey SL, Bromley SK, Johnson KG, Dustin ML, and Green JM: Polar redistribution of the sialoglycoprotein CD43: implications for T cell function. J Immunol 2002, 168: 3740-3746.

Lee S, Hori Y, Groves J, Dustin ML, and Chakraborty A: Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation. Trends Immunol 2002, 23: 492.

Lee S, Hori Y, Groves J, Dustin M, and Chakraborty A: The synapse assembly model Trends Immunol 2002, 23: 500.

Tseng S and Dustin M: T-cell activation: a multidimensional signaling network. Curr Opin Cell Biol 2002, 14: 575.

Bromley, S. K. and M. L. Dustin (2002). Stimulation of naive T cell adhesion and immunological synapse formation by chemokine dependent and independent mechanisms. Immunology. 2002 Jul;106(3):289-98.

Antón, I. M., M. A. de la Fuente, et al. (2002). WIP Deficiency Reveals a Differential Role for WIP and the Actin Cytoskeleton in T and B Cell Activation.Immunity 16: 193-204.

Lee, K.-H., A. D. Holdorf, et al. (2002). "T Cell Receptor signaling precedes formation of the immunological synapse." Science 295: 1539-1542.

Wulfing, C., C. Sumen, et al. (2002). "Costimulation and endogenous MHC ligands contribute to T cell recognition." Nat Immunol 3(1): 42-7.

Bromley, S. K., A. Iaboni, et al. (2001). "The immunological synapse and CD28-CD80 interactions." Nat. Immunol. 2: 1159-1166.

Dustin, M. L., S. K. Bromley, et al. (2001). "Identification of "self" through two-dimensional chemistry and synapses." Annu.Rev.Cell Dev.Biol. 17: 133-157.

Bromley, S.K., W.R. Burack, K.G. Johnson, K. Somersalo, T.N. Sims, C. Sumen, M.M. Davis, A.S. Shaw, P.M. Allen, and M.L. Dustin. 2001. The immunological synapse. Annu Rev Immunol. 19:375-96.

Dustin, M.L., P.M. Allen, and A.S. Shaw. 2001. Environmental control of immunological synapse formation and duration. Trends Immunol. 22:192-4.

Dustin, M.L., and A.R. De Fougerolles. 2001. Reprograming T cells: the role of extracellular matrix in coordination of T cell activation and migration. Curr.Opin.Immunol. 13:286-290.

Johnson, K.G., S.K. Bromley, M.L. Dustin, and M.L. Thomas. 2000. A supramolecular basis for CD45 regulation during T cell activation. Proc.Natl.Acad.Sci.USA. 97:10138-10143.

Dustin, M.L., and A.C. Chan. 2000. Signaling takes shape in the immune system. Cell. 103:283-294.

Dustin, M.L., and J.A. Cooper. 2000. The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. Nature Immunology. 1:23-29.

Bromley, S.K., D.A. Peterson, M.D. Gunn, and M.L. Dustin. 2000. Cutting Edge: Hierarchy of Chemokine Receptor and TCR Signals Regulating T Cell Migration and Proliferation. J Immunol. 165:15-19.

Anton van der Merwe, P., S.J. Davis, A.S. Shaw, and M.L. Dustin. 2000. Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition. Semin Immunol. 12:5-21.

Shih, N.Y., J. Li, V. Karpitskii, A. Nguyen, M.L. Dustin, O. Kanagawa, J.H. Miner, and A.S. Shaw. 1999. Congenital Nephrotic Syndrome in Mice Lacking CD2-Associated Protein. Science. 286:312-315.

Mordue, D.G., N. Desai, M. Dustin, and L.D. Sibley. 1999. Invasion by Toxoplasma gondii establishes a moving junction that selectively excludes host cell plasma membrane proteins on the basis of their membrane anchoring. J Exp Med. 190:1783-92.

Grakoui, A., S.K. Bromley, C. Sumen, M.M. Davis, A.S. Shaw, P.M. Allen, and M.L. Dustin. 1999. The immunological synapse: A molecular machine controlling T cell activation. Science. 285:221-227.

Dustin, M.L. and Shaw, A.S. 1999. Costimulation: Building an immunological synapse. Science. 283:649-650.

Ding, Z.M., J.E. Babensee, S.I. Simon, H. Lu, J.L. Perrard, D.C. Bullard, X.Y. Dai, S.K. Bromley, M.L. Dustin, M.L. Entman, C.W. Smith, and C.M. Ballantyne. 1999. Relative contribution of LFA-1 and mac-1 to neutrophil adhesion and migration. J Immunol. 163:5029-38.

Davis, M.M., C. Wulfing, M.F. Krummel, P.A. Savage, J. Xu, C. Sumen, M.L. Dustin, and Y.H. Chien. 1999. Visualizing T-cell recognition. Cold Spring Harb Symp Quant Biol. 64:243-51.

Dustin, M.L. 1998. Making a little affinity go a long way: a topological view of LFA-1 regulation. Cell Adhes.Commun. 6:255-62.

Dustin, M.L., M.W. Olszowy, A.D. Holdorf, J. Li, S. Bromley, N. Desai, P. Widder, F. Rosenberger, P.A. van der Merwe, P.M. Allen, and A.S. Shaw. 1998. A novel adapter protein orchestrates receptor patterning and cytoskeletal polarity in T cell contacts. Cell. 94:667-677.

Shaw, A.S., and M.L. Dustin. 1997. Making the T cell receptor go the distance: a topological view of T cell activation. Immunity. 6:361-369.

Knorr, R., and M.L. Dustin. 1997. The LFA-1 I domain is a transient binding module for ICAM-1 and ICAM-3 in hydrodynamic flow. Journal of Experimental Medicine. 186:719-730.

Ganpule, G., R. Knorr, J.M. Miller, C.P. Carron, and M.L. Dustin. 1997. Low affinity of cell surface LFA-1 generates selectivity for cell-cell interactions. Journal of Immunology. 159:2685-2692.

Dustin, M.L., D.E. Golan, D.M. Zhu, J.M. Miller, W. Meier, E.A. Davies, and P.A. van der Merwe. 1997. Low affinity interaction of human or rat T cell adhesion molecule CD2 with its ligand aligns adhering membranes to achieve high physiological affinity. J.Biol.Chem. 272:30889-30898.

Dustin, M.L. 1997. Adhesive bond dynamics in contacts between T lymphocytes and glass supported planar bilayers reconstituted with the immunoglobulin related adhesion molecule CD58. J.Biol.Chem. 272:15782-15788.

Dustin, M.L., S.K. Bromely, Z. Kan, D.A. Peterson, and E.R. Unanue. 1997. Antigen receptor engagement delivers a stop signal to migrating T lymphocytes. Proc.Natl.Acad.Sci.USA. 94:3909-3913.

Baorto, D.M., Z. Gao, R. Malaviya, M.L. Dustin, A. van der Merwe, D. Lublin, and S.N. Abraham. 1997. Survival of FIMH-expressing Escherichia coli in macrophages after co-opting glycolipid trafficking pathways Nature. 389:636-639.

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