Training Program in Molecular Oncology and Immunology:
Overview
This program trains doctoral candidates in the areas of molecular oncology, viral oncology, virus-cell interaction, cellular, humoral and developmental immunology, innate immunity, immunochemistry, and molecular genetics. Research experience may be acquired in the following areas: tumor virus-cell interaction, regulation of gene expression, oncogenes and tumor suppressor genes, DNA repair, lymphomas, molecular biology of immunoglobulin genes, immunogenetics, autoimmune disease, interferon, interleukins, cytokines and growth factors, AIDS, and various problems in cellular, tumor, and parasite immunology.
Director: Angel
Pellicer, M.D.
Graduate Advisors: David
E. Levy, Ph.D.
del243@med.nyu.edu
212-263-8192
Susan
Smith, Ph.D.
smithsu@saturn.med.nyu.edu
212-263-2540
|
|
Fall |
Spring |
|
First Year |
á
Foundations of Cell
and Molecular
Biology I á
Elective á
Research in Pathology |
á
Foundations of Cell
and
Molecular Biology II á
Introductory
Immunology á
Research in Pathology |
|
Second Year |
á
Seminar in Pathology* á
Research in Pathology á
Elective |
á
Molecular Oncology á
Elective á
Seminar in Pathology* á
Research in Pathology |
|
Third Year |
á
Seminar in Pathology* á
Research in Pathology |
á
Work in Progress grad
student Seminar á
Research in Pathology |
|
Fourth Year Until Completion of Degree |
á
Work in Progress grad
student Seminar á
Research in Pathology |
|
Required
Courses
|
Recommended Courses |
|
Foundations of Cell and
Molecular Biology I & II |
Advanced Immunology |
|
Introductory Immunology |
Bioinformatics |
|
Molecular Oncology (offered
every Spring of even numbered years) |
Molecular Virology (offered
every Spring of odd numbered years) |
Following are two lists: the first is of molecular
oncology faculty and their research interests, and the second, a list of
immunology program faculty and their research interests.
Molecular
Oncology and Immunology Program:
Molecular
Oncology Faculty and Research Interests
|
Erika
Bach, Ph.D. |
The
Roles of the Jak-STAT Pathway in Drosophila |
|
Dafna
Bar-Sagi, Ph.D. |
Oncogene
Function In Pancreatic Cancer |
|
Claudio
Basilico, M.D. |
Signals
Controlling Cell Proliferation |
|
Peter
Brooks, Ph.D. |
Regulation
of Invasive Cellular Processes |
|
Moses
Chao, Ph.D. |
Mechanisms
of Neurotrophin Receptor Signaling |
|
Pamela
Cowin, Ph.D. |
Cell
Adhesion and Wnt Signaling |
|
Gregory
David, Ph.D. |
Chromatin
Modification during Development and Cancer |
|
Brian
Dynlacht, Ph.D. |
Regulation
of Mammalian Cell Cycle Progression |
|
Michael
Garabedian, Ph.D. |
Mechanism
of Steroid Hormone Receptor Action |
|
Eva
Hernando, Ph.D. |
Cell
Cycle Dysregulation In Mouse Models Of Sarcoma |
|
Stevan
Hubbard, Ph.D. |
Crystallographic
Studies of Receptor Tyrosine Kinases |
|
Hannah
Klein, Ph.D. |
Genomic
Instability and DNA Damage Checkpoints |
|
Peng Lee,
M.D., Ph.D. |
Androgen
Receptor and its Cofactors in Prostate and Breast Cancer |
|
David Levy, Ph.D. |
Signal
Transduction and Gene Expression in Cell Growth Control |
|
Daniel Meruelo, Ph.D. |
Genetic
Predispositions to Tumorigenesis and Potential Treatments |
|
Moosa
Mohammadi, Ph.D. |
Structural
and Functional Studies of Fibroblast Growth Factor (FGF) Receptors |
|
Michele Pagano, M.D. |
Regulation
of the Mammalian Cell Cycle and its Deregulation in Cancer |
|
Angel
Pellicer, M.D., Ph.D. |
Molecular
Alterations in Tumor Formation |
|
Mark
Philips, M.D. |
Processing
and Membrane Targeting of GTPases |
|
Daniel
Rifkin, Ph.D. |
Extracellular
Control of Growth Factor Action |
|
David Ron,
M.D. |
The
Cellular Adaptation to Proteotoxicity |
|
David
Roth, M.D., Ph.D. |
Mechanisms
of Antigen Receptor Gene Rearrangement, Maintenance of Genomic Stability, DNA
repair and Lymphomagensis |
|
Robert
Schneider, Ph.D. |
Altered
Regulation of Gene Expression in Carcinogenesis and Cell Stress |
|
Susan
Smith, Ph.D. |
Molecular
Mechanisms of Telomere Function |
|
George
Teebor, M.D. |
Molecular
Genetics and Enzymology of DNA Excision Repair |
|
Daniel
Turnbull, Ph.D. |
In-Vivo
Microimaging of Transgenic Mice |
|
David
Zagzag, M.D., Ph.D. |
Mechanisms
of Cerebral Vasculogenesis and Angiogenesis |
|
Edward
Ziff, Ph.D. |
Molecular
Mechanisms of Synaptic Regulation |
Molecular
Oncology and Immunology Program:
Immunology
Faculty
|
Iannis
Aifantis, Ph.D. |
Signaling
mechanisms in T lymphocyte development |
|
Ross
Basch, M.D. |
Developmental
hematology and immunology |
|
Nina
Bhardwaj, M.D., Ph.D. |
Immunobiology
of antigen presenting cells; cancer vaccine development |
|
Steven
Burakoff, M.D. |
Signal
transduction in activated T-cells |
|
Michael
Dustin, Ph.D. |
T
cell activation, migration and adhesion. Formation of the immunological
synapse. |
|
Adrian
Erlebacher, M.D., Ph.D. |
Immunological
tolerance at the maternal-fetal interface |
|
Alan
Frey, Ph.D. |
Function
of tumor infiltrating lymphocytes (TIL) in human breast cancer |
|
Hodaka
Fujii, M.D., Ph.D. |
Analysis
of cytokine signal transduction and mechanisms of lymphocyte proliferation
and differentiation by cytokine-inducible genes. |
|
Catarina
Hioe, Ph.D. |
T
cell lymphocyte function in HIV infection |
|
Michelle
Krogsgaard, Ph.D. |
T
cell receptor structure and function |
|
Suman
Laal, Ph.D. |
Pathogenesis
and diagnosis of Mycobacterium tuberculosis infection |
|
Juan
Lafaille, Ph.D. |
Pathogenesis
of autoimmune and allergic diseases |
|
David
Levy, Ph.D. |
Cytokine
signaling in innate immunity to viral infections |
|
David
Roth, M.D., Ph.D. |
Molecular
basis of V(D)J recombination |
|
Jane
Skok, Ph.D. |
Nuclear
organization of immunoglobulin genes |
|
Sergio
Trombetta, Ph.D, Pharm D. |
Dendritic
cell function in innate and adaptive immunity |
|
Susan
Zolla-Pazner, Ph.D. |
Immune
response to HIV and vaccine development |
Seminar
Speakers: Immunology Club 2005 - 2006
|
September 15, 2005 |
ÒAntibodies and their receptors: mechanisms for coupling innate and
adaptive immunityÓ Jeffrey Ravetch, M.D., Ph.D. The Rockefeller University |
|
November 17, 2005 |
ÒIn silico and
experimental approaches to study the immunological synapseÓ Andrey Shaw, M.D. Washington University |
|
September 22, 2005 |
ÒMolecular mechanisms of lineage commitment in the
spleen and a novel functional niche for B cellsÓ Shiv Pillai, M.D, Ph.D. Harvard University |
|
December 1, 2005 |
ÒAn unexpected mechanism prompting organ-specific
autoimmunity diseaseÓ Diane Mathis, Ph.D. Harvard Medical School |
|
September 29, 2005 |
ÒEndogenous and exogenous glycosphingolipid antigens
for NKT cells during microbial infection.Ó Albert Bendelac, M.D., Ph.D. University of Chicago |
|
December 8, 2005 |
ÒDendritic Cells and ImmunityÓ Yong-Jun Liu, M.D., Ph.D. M.D. Anderson Cancer Ctr. |
|
October 6, 2005 |
ÒThe Complexities of the Leukocyte Recruitment
ParadigmÓ Paul Kubes M.D, Ph.D. University of Calgary |
|
December 8, 2005 |
ÒDendritic Cells and ImmunityÓ Yong-Jun Liu, M.D., Ph.D. M.D. Anderson Cancer Ctr. |
|
October 13, 2005 |
ÒClass switch recombination and somatic
hypermutation study through human natural mutantsÓ Anne Durandy, M.D., Ph.D. Hospital Necker-Enfants Malades |
|
January 5, 2006 |
ÒImmunoregulation of Dendritic Cells by Activating
and Inhibitory Fc Receptors.Ó Raphael Clynes, M.D., Ph.D. Columbia University |
|
October 20, 2005 |
ÒDNA-PKcs: Director at the EndÓ Katheryn Meek, D.V.M. Michigan State University |
|
January 12, 2006 |
ÒMechanisms of Th1 Effector CD4 Cell Tolerization,
and the Effect of Prostate Tumorigenesis on CD4 Cell ToleranceÓ Adam Adler, Ph.D. University of Connecticut School of Medicine |
|
November 3, 2005 |
ÒMolecular Mechanisms of Antigen ProcessingÓ Peter Cresswell, Ph.D. Yale University School of Medicine |
|
January 19, 2006 |
ÒTh17; A New Lineage of Effector CD4 T cellsÓ Casey Weaver, M.D. University of Alabama at Birmingham |
|
November 10, 2005 |
ÒA Role for Toll-like Receptors in Systemic
Autoimmune DiseasesÓ Ann Marshak-Rothstein, Ph.D. Boston University, School of Medicine |
|
January 26, 2006 |
ÒRole of p38 MAP kinase in thymocyte developmentÓ Mercedes Rincon, Ph.D. University of Vermont |
|
February 9, 2006 |
ÒPerivascular cells: immunological regulators of the
central nervous systemÓ William Hickey, M.D. Dartmouth Medical School |
|
April 20, 2006 |
ÒS1P and lymphocyte egress controlÓ Jason Cyster, Ph.D. University of California San Francisco |
|
February 16, 2006 |
ÒSpecial Delivery: A New Model for PerforinÓ Judy Lieberman, M.D., Ph.D. Harvard Medical School |
|
April 27, 2006 |
ÒSecretion at the immunological synapseÓ Gillian Griffiths, PhD Sir William Dunn School of Pathology |
|
February 23, 2006 |
ÒFrom stem cell to T cell: one route or many?Ó Avinash Bhandoola, M.D., Ph.D. University of Pennsylvania, School of Medicine |
|
May 4, 2006 |
ÒUbiquitin, NF-kB and Antiviral Innate ImmunityÓ Zhijian Chen, Ph.D. University of Texas - SW Medical Center |
|
March 2, 2006 |
ÒHarnessing innate immunity in the adaptive
anti-tumor immune response. Ó Willem Overwijk, Ph.D. M.D. Anderson Cancer Center |
|
May 11, 2006 |
ÒPeripheral tolerance of CD8 T cells to self and
tumor antigensÓ Linda A. Sherman, Ph.D. The Scripps Research Institute |
|
March 9, 2006 |
ÒInsights into the molecular mechanisms of CD4 T
cell differentiation in the thymusÓ Remy Bosselut, M.D., Ph.D. National Cancer Institute, NIH |
|
May 18, 2006 |
ÒSystemic immune tolerance and autoimmunityÓ Abul Abbas, M.D. University of California, San Francisco |
|
March 16, 2006 |
ÒGeneration and localization of gut tropic effector
T cells.Ó William Agace, Ph.D. Lund University, Sweden |
|
May 25, 2006 |
ÒLymphocyte cytoskeleton and its rapid
reorganization in response to chemokine: ERMs and beyond.Ó Steve Shaw, M.D. Chief, Human Immunology Section, NCI, NIH |
|
March 23, 2006 |
"The biology of gamma c-family of cytokines and
the IL-7 related cytokine, TSLP" Warren Leonard, Ph.D. National Heart, Lung and Blood Institute (NHLBI) |
|
June 1, 2006 |
ÒCheckpoints of autoimmunity: tracking of
encephalitogenic effector T cells in living milieusÓ Alexander Flugel, M.D. Max-Planck Institute for Neurobiology |
|
March 30, 2006 |
ÒTRAF6, a regulator of the osteoimmune systemÓ Yongwon Choi, Ph.D. University of Pennsylvania, School of Medicine |
|
June 8, 2006 |
ÒTwo mechanisms of regulating T cell activation and
homeostasis: Foxo and caspase-8Ó Steve Hedrick, Ph.D. University of California, San Diego |
|
April 6, 2006 |
ÒActivation and sequestration of CD8+ T cell in
liverÓ Nicholas Crispe, Ph.D. University of Rochester |
|
June 15, 2006 |
ÒT cell activation and the Immunological Synapse: a
view from the centerÓ Abraham (Avi) Kupfer, Ph.D. Johns Hopkins University School of Medicine |
|
April 13, 2006 |
ÒModulating vaccine responses with innate immunityÓ Bali Pulendran, Ph.D. Emory Vaccine Center |
|
June 22, 2006 |
ÒMetabolic and Genetic regulation of T cell function
and Autoimmunity via the Hexosamine and N-glyosylation Pathways.Ó Michael Demetriou, M.D. University of California, Irvine |