Week 4 - Molecular machines

Instructor:
David Stokes
Skirball 3-13
x3-1580
stokes@saturn.med.nyu.edu

Reading assignment:
For Mon. Oct 4th:
Branden and Tooze: pp. 191-194 (leucine zipper), pp. 251-260 (G proteins), pp. 290-298 (myosin)
Geeves, M.A. & K.C. Holmes. 1999. Structural Mechanism of Muscle Contraction. Annu. Rev. Biochem. 68:687-728 (pp. 687-718 most relevant for us)
Vale & Milligan. 2000. Science 288:88-95

For Wed. Oct 6th:
Oster, G. & H. Wang. 1999. ATP synthase: two motors, two fuels. Structure 7:R67-R72.
Stokes & Green. 2003. Annu Rev Biophys Biomol Struct. 32:445-68.
This contains far too much detail - you won't want to read the whole thing.

Discussion paper:
Kikkawa et al., Nature 411, 439-445 (2001)

Lectures:
Myosin and Kinesin
F0F1 ATPase and Ca-ATPase

Student feedback:
Survey form