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Structure of the Synapse
Friday, June 05, 2009 The 2009 Skirball Symposium is open to the public, with no registration fee. We are our synapses. A synapse is the site where neurons meet and communicate with each other. It is also the place where defects in architecture or communication cause diseases like Alzheimer's and Parkinson's. Most drugs known to affect the brain exert their therapeutic effects at the synapse. Therefore, studying synaptic architecture and transmission mechanism is crucial for an understanding of physiologic processes - learning and memory - and disease pathogenesis. In recent years, great progress has been made in identifying the major components of the synapse and their interplay: vesicle fusion proteins, scaffolding proteins, neurotransmitter transporters, receptors and channels. The 2009 Skirball Symposium, "Structure of the Synapse," will bring together some of the world's leading experts in this field to review the most recent breakthroughs in synaptic structure and mechanism, and how such work will impact the clinical disciplines of neurology, psychiatry and neuropharmacology. Program
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